Ascorbyl tetraisopalmitate is a stable, oil-soluble form of vitamin C that is less irritating to the skin than other forms of vitamin C. It is a potent antioxidant and anti-inflammatory that helps to protect the skin from oxidative stress, inflammation, and the aging process. It is also known as VC-IP.
Ascorbyl tetraisopalmitate offers a range of benefits for the skin: * Antioxidant and anti-inflammatory: It helps to protect the skin from oxidative stress and inflammation. * Collagen and elastin synthesis: It is necessary for the synthesis and maintenance of collagen and elastin. * Skin barrier function: It is necessary for the formation of the skin barrier function. * Blood flow: It stimulates blood flow to the skin. * UV protection: It protects the skin from UV light. * Hyperpigmentation: It inhibits the activation of the enzyme tyrosinase, which prevents the overproduction of melanin and helps to control and treat hyperpigmentation. * Remains in the skin cells forty to eighty times longer than L-ascorbic acid and will have as much as four times the effect. * Allows for faster percutaneous absorption than other forms of vitamin C—cells absorb 10 times the concentration of ATIP compared to L-ascorbic acid. * Is a proven precursor of Vitamin C and effectively suppresses UVB-induced skin pigmentation. * Reduces trans-epidermal water loss, increases skin elasticity, and visibly improves skin texture. * It's more gentle on sensitive skin and helps hydrate the skin by stimulating it to make its natural moisturizers called glycosaminoglycans. * It's more effective and bioavailable than other forms of Vitamin C and can be used in higher doses. It is a powerful antioxidant and also helps clear pigmentation. * It's more stable in air and water for up to 18 months, making it more effective once it leaves the bottle. * Triple action on aging - acts on cell renewal, improves hydration and has a tensor effect * Inhibits lipid peroxidation in acne-prone skin * Potent antioxidative comedogenic compound reducer * Vitamin C with greater percutaneous absorption * Helps prevent skin aging * Helps promote collagen synthesis and protection * SOD-like activity (Superoxide dismutase) * Reduces cellular DNA damage induced by UV radiation * Helps to even out skin tone by favoring the inhibition of tyrosinase activity and antioxidant action * Stable at high temperatures.
Suitable for all skin types, especially those with sensitive skin or a compromised acid barrier.
Ascorbyl tetraisopalmitate is generally well-tolerated, but some people may experience mild irritation, especially at higher concentrations.
Ascorbyl tetraisopalmitate is sensitive to heat and light, so it should be stored in a cool, dark place. It should also be used at a pH of 3.5 or lower to ensure stability.
Ascorbyl tetraisopalmitate is a derivative of ascorbic acid and isopalmitic acid.
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Ascorbyl tetraisopalmitate is approved as a quasi-drug active in Japan at 3% concentration and is registered in Korea as a functional ingredient for skin brightening at 2% concentration. Ascorbyl tetraisopalmitate is often compared to tetrahexyldecyl ascorbate (THDA), another oil-soluble form of vitamin C. While they have many similarities, they are each their own unique chemical. ATIP is a bit trickier to produce, which may have impacts on functions such as skin permeability—justifying its higher price. ATIP also claims more extensive efficacy data showing impressive results even at low usage levels, where THDA is not quite as well studied. Ascorbyl tetraisopalmitate is a stable form of vitamin C that is less irritating to the skin than other forms of vitamin C. It is a potent antioxidant and anti-inflammatory that helps to protect the skin from oxidative stress, inflammation, and the aging process. It is also known as VC-IP. Ascorbyl Tetraisopalmitate is a stabilized (heat and oxygen stable), non-acidic, oil soluble Vitamin C derivative of Ascorbic and Isopalmitic Acid. It effectively converts into the free Vitamin C in the skin. Ascorbyl Tetraisopalmitate is known for its superior percutaneous absorption due to being oil soluble. It’s an antioxidant with SOD (superoxide dismutase)-like activity, protects collagen from degradation, and also promotes its synthesis (anti-ageing). Ascorbyl Tetraisopalmitate is approved as a quasi-drug active in Japan at 3%. It is also registered in Korea as a functional ingredient for skin lightening at 2% concentration. Why Ascorbyl Tetraisopalmitate? What About Pure Ascorbic Acid? The skincare benefits of Vitamin C are well-researched and well-known. But, there are a few problems with the use of pure Vitamin C aka Ascorbic Acid: Vitamin C is an unstable molecule, undergoes rapid oxidation, and almost half of it gets degraded within 30 minutes which is why earlier traditional formulas needed to have higher percentages. It can be stabilized to some degree by keeping it at low pH (below 3.5) and by adding other antioxidants to the formula (Vitamin E, Ferulic acid). When taken orally or applied to the skin, most of the Vitamin C never makes it to the skin's cells. Also, it is difficult to deliver Ascorbic Acid into the dermis in the optimum dosage. Ascorbic Acid requires low pH (acidic) environment to be able to penetrate the skin, which can cause irritation such as peeling, stinging and excessive dryness. Ascorbyl Tetraisopalmitate - A More Potent and Stable Vitamin C Derivative Due to Vitamin C's infamous instability, many derivatives have been produced. One such derivative is Ascorbyl Tetraisopalmitate. When compared to pure Vitamin C (Ascorbic Acid), this derivative is: * More stable, both in solution and topical forms. * Has three times better penetration than ascorbic acid. * Is able to produce better results even when used in doses 25 times lower than ascorbic acid. Skincare benefits What benefits should you expect following the use of Ascorbyl Tetraisopalmitate? - It is a potent antioxidant and inhibits the peroxidation of lipids. When compared to simple Ascorbic Acid, Ascorbyl Tetraisopalmitate was able to exert free-radical scavenging effects for a longer duration (up to 40 hours). Ascorbic acid, on the other hand, caused maximum free radical elimination within 30 minutes and not after that. - It has anti-ageing benefits by improving collagen production and decreasing collagen breakdown. In comparison to Ascorbic Acid, a provides a 50% increase in collagen synthesis. - Protects the skin against UV (Ultraviolet) radiations. Ascorbyl Tetraisopalmitate achieves an excellent penetration within the skin keratinocytes and helps them fight against the harmful effects of UV radiation. Cells treated with Ascorbyl Tetraisopalmitate have a 30% better survival rate compared to pure vitamin C. p53 is a cellular protein that makes your body cells commit suicide (apoptosis). When treated with Ascorbyl Tetraisopalmitate, the UV-exposed cells have a less than 20% expression of p53 compared to control. - Has major skin brightening properties by reducing melanogenesis by 80%, unlike other Vitamin C derivatives.