Methylchloroisothiazolinone (MCI) and Methylisothiazolinone (MI) are preservatives used in cosmetics and personal care products to prevent microbial growth. MCI is often combined with MI under the brand name Kathon CG. They can cause skin irritation and allergic reactions, especially when used in high concentrations.
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MCI and MI can cause skin irritation and allergic reactions, especially when used in high concentrations. It can also cause contact dermatitis, which can lead to redness, swelling, raised bumps or hives, red patches on lighter skin, grey, purple, or brown patches on darker skin, itchiness, flaky skin, eye swelling, and peeling skin.
People who are allergic to MCI or MI should avoid using products that contain them. It is important to read labels carefully and avoid products that list MCI or MI as an ingredient. If you experience any skin irritation or allergic reaction after using a product that contains MCI or MI, stop using the product immediately and consult a doctor.
Synthetically produced.
CIR has assessed the safety of MCI and MI several times. In 2010, the CIR Expert Panel concluded that MCI and MI were safe for use as cosmetic ingredients at concentrations up to 100 ppm. However, in 2013, the CIR Expert Panel reopened the safety assessment of MI due to concerns about an increase in skin allergy reactions to MI. The Panel concluded that MI use in many leave-on product categories would be safe only at concentrations lower than 100 ppm and only when it could be demonstrated that the concentration used does not cause allergic skin reactions.
EWG has rated MCI as a moderate hazard ingredient.
MCI and MI are often used together in a mixture called Kathon CG. Kathon CG is a broad-spectrum preservative that is effective against a wide range of microorganisms. It is used in a variety of cosmetic and personal care products, including shampoos, conditioners, body washes, and lotions. MCI and MI can also be found in industrial products, such as paints, adhesives, and metalworking fluids.
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